Raastargeting drugs reninangiotensin system important role in regulating blood volume, arterial pressure, and cardiac and vascular function. Pharmacodynamics digitalis is most frequently used to increase the adequacy of the circulation in patients with ccf and to slow the ventricular rate in patients with atrial fibrillation or flutter nb. Jcpt also features commentaries written by respected investigators in the field. Find powerpoint presentations and slides using the power of, find free presentations research about cardiovascular pharmacology ppt. Specific indications for particular drugs are discussed in other relevant chapters. Five reasons to publish your article in cardiovascular drugs and therapy. Learn pharm quiz 2 pharmacology cardiovascular drugs with free interactive flashcards. Pharmacology comprises some broad conceptions and generalizations, and some detailed conclusions, of such great and practical importance that every student and practitioner of medicine should be absolutely familiar with them. Reid college of science, engineering and health, rmit university, melbourne, vic 3001, australia keywords. Examples of disorders in which such drugs may be useful include hypertension high blood pressure, angina pectoris chest pain resulting from inadequate blood flow through the coronary arteries to the heart muscle.
Zvara, md antiischemic drug therapy antiischemic drug therapy during anesthesia is indicated whenever evidence of myocardial ischemia exists. Cardiovascular pharmacology cardiovascular circulatory system heart and blood vessels arteries transport blood to tissues capillaries sites of exchang slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Most important site for renin release is the kidney. Powerpoint presentation on cardiovascular pharmacology. Examples of disorders in which such drugs may be useful include hypertension high blood pressure, angina pectoris chest.
Cardiovascular drugs and therapy is a careful and accurate guide through the maze of new products and therapies which furnishes you with the details on cardiovascular pharmacology that you will refer to time and time again. Management depends on the type of angina and may include drug treatment, coronary artery bypass surgery, or percutaneous transluminal coronary angioplasty. Garret gross and were published in the division for cardiovascular pharmacology, a branch of the american society for pharmacology and experimental. Enalaprilat itself is available only for intravenous use, primarily for hypertensive emergencies. During intravenous therapy with ntg, if blood pressure bp drops and ischemia is not relieved, the addition of phenylephrine will allow coronary perfusion pressure cpp to be maintained while allowing higher doses of ntg to be used for ischemia relief. Download cardiovascular pharmacology download free online book chm pdf. Clinical application mechanism of action drug of choice doc eg.
Drugs that act on the cardiovascular system are among the most widely used in medicine. The content emphasizes the biophysical, biochemical, and cellular basis for drug therapy. Clinical pharmacology of cardiovascular drugs oxford. The website also includes short quizzes on various pharmacological topics and medication areas. Review of cardiovascular form and function introduction and background cardiovascular disease is the major cause of death in the us 50% of all deaths cardiovascular function based on cardiac pumping ability pacemaking electrical signals force of contraction height of ventricle discharge pressure integrity of vasculature presence of blockage muscular tone. A free powerpoint ppt presentation displayed as a flash slide show on id. A healthy cardiovascular system is essential to overall health and wellness. Pharmacology cardiovascular drugs free download as powerpoint presentation. Antiarrhythmic drugs treatment of arrhythmias requires precise diagnosis of the type of arrhythmia, and electrocardiography is essential. Ivms 20042008 1 ivms cardiovascular pharmacology lecture topics discussed.
Myocardial preconditioning, nitrates tolerance how to avoid it,contraindications. Ct publishes papers that will elucidate the effects, molecular mechanisms, and signaling pathways of environmental toxicants on the cardiovascular system. Antiarrhythmic drugs must be used cautiously since most drugs that are effective in. Garret gross and were published in the division for cardiovascular pharmacology, a branch of the american society for pharmacology and experimental therapeutics aspet antianginal drugs lecture. Review of cardiovascular form and function introduction and background cardiovascular disease is the major cause of death in the us 50% of all deaths cardiovascular function based on cardiac pumping ability pacemaking electrical signals force of contraction height of ventricle discharge pressure integrity of vasculature presence of blockage. Ratelimiting agents have greater activity on cardiac muscle and so reduce the force of cardiac contraction and heart rate see chapter 12. Rational prescribing informed by clinical pharmacology is essential if the right drug is to be. Cardiovascular disease including heart disease, arrhythmias and hypertension, is the leading cause of morbidity and mortality in the western world.
Some examples of the drugs used in cardiovascular medicine include. There are several classes of established lipidlowering, or antihyperlipidemic drugs available to the prescriber. The free ebook has 14 sections and these are listed as below. Pharmacology cardiovascular drugs cardiac arrhythmia. The guide goes into extensive detail on exactly what you need to do to safely, effectively and permanently get rid of gout, and you are guaranteed to see dramatic improvements in days if not hours.
During intravenous therapy with ntg, if blood pressure bp drops and ischemia is not relieved, the addition of phenylephrine will allow coronary perfusion pressure cpp to be maintained while allowing. Alright, now in this part of the article, you will be able to access the free pdf download of basic concepts in pharmacology 4th edition pdf using our direct links mentioned at the end of this article. Antihypertensive drugs drugs for angina ace inhibitors calcium channel blockers adrenergic blockers cardiac glycosides prepared and presented by. Clicking on the drug class will open a new window providing detailed information on. Treatment of cardiovascular cv disease often requires the administration of numerous medications for long periods of time to patients likely to be old and suffering from a range of comorbid conditions. Choose from 500 different sets of pharmacology cardiac drugs flashcards on quizlet. Cardiovascular system pharmacology education project. Pharmacology introduction to pharmacology drugs should be used to prevent, to cure and to diagnose diseases. The growth in the cardiovascular drugs market is due to increase in aging population, increase in the prevalence of cardiovascular diseases and availability of more generic drugs that reduce the.
This journal is a member of the committee on publication ethics cope. Phenylalkylamines, benzothiazepines, 1,4dihydropyridines. Enalapril is an oral prodrug that is converted by hydrolysis to an active compound, enalaprilat, with effects similar to those of captopril. This presentation on calcium channel blockers was created by dr. Download this books into available format 2019 update. Choose from 500 different sets of pharm quiz 2 pharmacology cardiovascular drugs flashcards on quizlet. This lesson outlines some of the most common cardiovascular disorders and the medications used to manage them. There are numerous devastating conditions affecting the heart andor the vasculature, leading to high demand for cardiovascular drugs. Pharmacology of cardiovascular drugs johns hopkins. It will increase your awareness of controversies in. May 23, 2011 the gout eraser is a short, to the point guide on how to reverse gout symptoms without ever leaving your home. Hld drugs mechanism of action clinical use side effects statins inhibit hmgcoa reductase, modify platelets and endothelium, suppress inflammation lower ldl 1st line for hyperlipidemia myopathy, hepatotoxicity, drug interactions ezetimibe inhibit npc1l1 at brush border in small inte.
Kd tripathi pharmacology ebook download free in pdf format. Cardiac pharmacology is grouped under seven categories as per their physiological actions antiadrenergic drugs, anti arrhythmic drugs, antithrombotic drugs, diuretics, inotropic drugs, lipid regulating drugs and vasodilator. Rational prescribing informed by clinical pharmacology is essential if the right drug is to be administered to the right patient, at the right time, and for the right price. It was published on the aspet cardiovascular division website calcium channel blockers ppt outline introduction classification. Abdelmotaal fouda, associate professor of clinical pharmacology, mansoura faculty of medicine.
Approach to cvs pharmacology learn agents by drug classes eg. A manual of pharmacology and its applications to therapeutics and toxicology. This webpage provides information around the history and development of beta blocker drugs, their pharmacology, mechanism of action, pharmacokinetics and adverse effects. The gout eraser is a short, to the point guide on how to reverse gout symptoms without ever leaving your home. A wide range of medications are used to treat various heart conditions. All references in the book are available to download for free. Nov 25, 2016 video lectures in clinical pharmacology by dr. Autonomic nervous system the patient is 21 yrs old and has experienced frequent episodes of blurred vision, dizziness, faintness and syncope for as long as she can remember.
Journal of cardiovascular pharmacology and therapeutics. Raastargeting drugs reninangiotensin system angiotensin ii constricts vessels thereby increasing vascular resistance and arterial pressure stimulates the adrenal cortex to release aldosterone, which acts upon the kidneys to increase sodium and fluid retention stimulates the release of vasopressin antidiuretic hormone, adh from the pituitary which acts upon the kidneys to increase fluid retention facilitates norepinephrine release and. Ppt cardiovascular drugs powerpoint presentation free. Learn pharmacology cardiac drugs with free interactive flashcards. Cardiac glycosides drugs originally obtained from plant source, digitalis purpurea and digitalis lanata digoxin and digitoxin are the only cardiac glycosides currently available main pharmacologic effect of cardiac glycosides is to increase the contractile force of myocardial contraction cardiac glycosides also decrease heart. Scribd is the worlds largest social reading and publishing site. Enzyme inhibition, steroids, adrenocorticoids, cardiac glycosides, oral hypoglycemic agents, drug design, cardiovascular drugs, steric effects and drug action, enzyme action, biophysical approaches to drug design. Captopril is the shortacting active prototype of this group.
The following cardiovascular pharmacology presentation is a practical overview on hypertension, drugs used in heart failure, mi, shock and antiarrhythmics. The questions contained in this short multiplechoice quiz will test your knowledge of pharmacology of the cardiovascular system. Cardiovascular drug, any agent that affects the function of the heart and blood vessels. They are also used as class iv antiarrhythmics chapter 12. Ppt cardiovascular drugs powerpoint presentation free to. The cardiovascular pharmacology of cox2 inhibition. Journal of cardiovascular pharmacology and therapeutics jcpt provides clinical and basictranslational investigators with novel insights into stateoftheart therapeutic approaches for cardiovascular diseases. Cardiovascular drugs for pharmacology final author. However, it seems likely that differences in the degree of selectivity attained by various drugs may translate into quantitative differences in clinical outcomes. The following set of pharmacology lectures has been created by dr. The coronary arteries supply oxygenladen blood from. University of kentucky department of anesthesiology.
Cardiovascular drugs 119 dihydropyridines are selective for calcium channels on vascular smooth muscle and so cause vasodilatation. Pharmacodynamic these are largely predictable from a basic understanding of cardiovascular pharmacology. Cardiovascular and renal pharmacology sheila a doggrell and julianne j. Cardiovascular pharmacology hypertension angina pectoris. This site describes drugs that are used in the treatment of cardiovascular disease.
Mouse biology, human pharmacology, and clinical evidence suggest that the cardiovascular hazard pertains to all coxibs. Ppt cardiovascular pharmacology powerpoint presentation. Jun 05, 2017 cardiovascular pharmacology cardiovascular circulatory system heart and blood vessels arteries transport blood to tissues capillaries sites of exchang slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Indirect actions of digitalis many of the effects of digitalis on the mechanical and electrical activity of the heart in situ, result. View cardiac pharmacology ppts online, safely and virusfree. Antianginal drugs the three main types of angina are. The growth in the cardiovascular drugs market is due to increase in aging population, increase in the prevalence of cardiovascular diseases and. View and download powerpoint presentations on cardiovascular pharmacology ppt. Cardiac pharmacology is grouped under seven categories as per their physiological actions antiadrenergic drugs, anti arrhythmic drugs, antithrombotic drugs, diuretics, inotropic drugs, lipid regulating drugs. This chapter includes a discussion of the first four categories. Nevertheless, the following list attempts to classify drugs based on their dominant mechanism of action, or by the mechanism that is the most therapeutically relevant for cardiovascular disease.
Cardiovascular pharmacology 10 congestive heart failure. Anticoagulants or blood thinners these agents prevent. Set 1 powerpoint links collected from the website of. Researchers in the department exploit novel technologies such as induced pluripotent stem cells, automated electrophysiology and genomics to investigate the causes of sudden cardiac death, congenital. Cardiovascular pharmacology focuses on the fundamental mechanisms of cardiovascular cells and how drugs influence the heart and vascular system. Clinical pharmacology of cardiovascular drugs oxford medicine. Guidelines for the reintroduction of medications following routine cardiac surgery are provided in chapter 17. Jun 20, 2019 a wide range of medications are used to treat various heart conditions. Ivms heart and circulation lecture an integrated basic medical sciences perspective and presentation.
Antianginals are pharmaceutical agents used to treat angina pectoris, a disease of the coronary arteries. Cardiovascular drugs can be broadly categorized as 1 antianginals, 2 antiarrhythmics, 3 antihypertensives, 4 anticoagulants, 5 antihyperlipidemic agents, 6 hypoglycemic agents, and 7 antithyroid drugs and thyroid hormones. The focus of the experimental studies is translational research. Basic concepts in pharmacology 4th edition pdf free download.
Bimm118 antihypertensive drugs potential drug targets. Cv pharmacology welcome to cardiovascular pharmacology concepts. Cardiovascular pharmacology powerpoint template demplates. May 18, 2015 cardiovascular medicines have advanced from what they were two decades back owing to the advancements and developments in genetics, molecular biology and biophysics. Cardiovascular medicines have advanced from what they were two decades back owing to the advancements and developments in genetics, molecular biology and biophysics. The quiz is scored automatically and can be taken multiple times. Ace inhibitors, aldosterone receptor antagonists, angina, antianginal agents, antiarrhythmic drugs, anticoagulant drugs, antihyperlipidemic drugs, anti. Powerpoint presentation on cardiovascular pharmacology for. Welcome to cardiovascular pharmacology concepts richard e. Cv pharmacology welcome to cardiovascular pharmacology.
1135 830 1479 1054 714 1486 65 347 1559 1536 1134 430 1056 178 575 191 944 130 7 351 106 656 1620 200 1075 1479 1339 587 1421 135 280 1440 766 544 522 1169